Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809786 | 0.92 | HDAC3 (0.50) | HTR6CNR2TBXAS1HDAC3CNR1 | |
| SCHEMBL9701802 | 0.88 | HTR6 (0.64) | HTR6HDAC3LMNAHDAC1HDAC8 | |
| SCHEMBL7815554 | 0.82 | HDAC1 (0.49) | HTR6CNR2HDAC3CNR1HTR2C | |
| SCHEMBL7811888 | 0.81 | CAMK2D (0.51) | CNR2TBXAS1CNR1 | |
| SCHEMBL7809789 | 0.80 | TBXAS1 (0.51) | TBXAS1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL7803155 | 0.74 | CAMK2D (0.52) | CNR2TBXAS1CNR1ICMT | |
| SCHEMBL7809792 | 0.72 | HDAC6 (0.62) | CNR2HDAC3CNR1HTR2CLMNA | |
| SCHEMBL7803160 | 0.71 | APP (0.56) | CNR2HDAC3CNR1HTR2CKDM4E | |
| SCHEMBL31370014 | 0.70 | KMT2A (0.55) | CNR2CNR1HTR2CKDM4ELMNA | |
| SCHEMBL8544039 | 0.69 | TBXAS1 (0.52) | HTR6CNR2TBXAS1HDAC3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |