⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816856 | 0.75 | MMP2 (0.31) | — | |
| SCHEMBL8297646 | 0.73 | CHRNA3 (0.38) | — | |
| SCHEMBL7817737 | 0.72 | MMP2 (0.35) | — | |
| SCHEMBL24591445 | 0.71 | LTA4H (0.40) | — | |
| SCHEMBL7810422 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL7819136 | 0.69 | MMP2 (0.31) | — | |
| SCHEMBL7821671 | 0.67 | MMP2 (0.33) | — | |
| SCHEMBL40277 | 0.66 | — | — | |
| SCHEMBL7819246 | 0.66 | CA12 (0.34) | — | |
| SCHEMBL7808528 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798298-B1 | THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO CO (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-5843973-A | Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0798298-A1 | THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |