Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826265 | 0.86 | CSNK2A1 (0.41) | PARP1CSNK2A1DYRK1AKIF11KMT2A | |
| SCHEMBL7825719 | 0.82 | CSNK2A1 (0.37) | PARP1CSNK2A1DYRK1AKIF11ALDH1A1 | |
| SCHEMBL8058133 | 0.80 | KMT2A (0.40) | PARP1DYRK1AALDH1A1KMT2AKDM4E | |
| SCHEMBL7826292 | 0.80 | KDM4E (0.47) | DYRK1AALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL7826963 | 0.79 | TTR (0.41) | PARP1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL7823420 | 0.79 | DYRK1A (0.44) | DYRK1AALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL7831864 | 0.79 | KDM4E (0.40) | DYRK1AALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7826959 | 0.79 | TTR (0.41) | PARP1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL8073487 | 0.79 | MAOA (0.55) | KIF11ALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL7827947 | 0.78 | PTGES (0.43) | PARP1KIF11ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |