Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.51 |
| ▸ | FEN1 | P39748 | 2/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831194 | 0.85 | MAPT (0.58) | POLBMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7826265 | 0.84 | CSNK2A1 (0.41) | MAOAKIF11KDM4EKMT2A | |
| SCHEMBL7815301 | 0.81 | KDM4E (0.42) | MAOAMAPTTDP1KDM4EALDH1A1 | |
| SCHEMBL7817176 | 0.79 | PARP1 (0.55) | KIF11POLBKDM4EALDH1A1HPGD | |
| SCHEMBL7827947 | 0.78 | PTGES (0.43) | CHEK1KIF11POLBKDM4EALDH1A1 | |
| SCHEMBL7831634 | 0.78 | GAA (0.42) | CHEK1POLBTDP1KDM4EALDH1A1 | |
| SCHEMBL7822908 | 0.77 | KDM4E (0.38) | MAOAPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL7822903 | 0.77 | IAPP (0.38) | MAOACHEK1TDP1 | |
| SCHEMBL7826811 | 0.76 | ALDH1A1 (0.40) | MAOAPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL8073271 | 0.76 | PARP1 (0.50) | CHEK1KIF11MAPTBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |