Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 9/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817176 | 0.86 | PARP1 (0.55) | CSNK2A1KIF11PARP1DYRK1AKDM4E | |
| SCHEMBL8073487 | 0.84 | MAOA (0.55) | KIF11MAOAKDM4EKMT2A | |
| SCHEMBL7831634 | 0.81 | GAA (0.42) | KDM4EGAAKMT2A | |
| SCHEMBL7827947 | 0.81 | PTGES (0.43) | KIF11PARP1KDM4EKMT2A | |
| SCHEMBL7831194 | 0.81 | MAPT (0.58) | KDM4ETP53KMT2A | |
| SCHEMBL7825719 | 0.81 | CSNK2A1 (0.37) | CSNK2A1KIF11PARP1DYRK1AIMPDH2 | |
| SCHEMBL7822903 | 0.80 | IAPP (0.38) | CSNK2A1MAOA | |
| SCHEMBL7822908 | 0.80 | KDM4E (0.38) | PARP1DYRK1AMAOAKDM4ETP53 | |
| SCHEMBL7815301 | 0.79 | KDM4E (0.42) | PARP1IMPDH2MAOAKDM4EKMT2A | |
| SCHEMBL7826811 | 0.79 | ALDH1A1 (0.40) | DYRK1AMAOAKDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |