Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817420 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1GAALMNAL3MBTL1 | |
| SCHEMBL7813660 | 0.82 | MAPT (0.56) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL7811730 | 0.81 | LMNA (0.50) | MAPTALDH1A1LMNAHTT | |
| SCHEMBL7811396 | 0.81 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAKDM4EHTT | |
| SCHEMBL9011142 | 0.80 | MAPT (0.42) | MAPTALDH1A1GAALMNAKCNA5 | |
| SCHEMBL7814074 | 0.80 | SMN1; SMN2 (0.53) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL7811456 | 0.80 | MAPT (0.49) | MAPTALDH1A1LMNAHTT | |
| SCHEMBL7814066 | 0.80 | ALDH1A1 (0.54) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL7813608 | 0.80 | MAPT (0.57) | MAPTALDH1A1LMNAHTT | |
| SCHEMBL7810031 | 0.80 | MAPT (0.49) | MAPTALDH1A1GAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |