Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.31 |
| ▸ | TUBB | P07437 | 3/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818360 | 0.84 | PTGS2 (0.45) | MAPTHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL7815128 | 0.84 | PTGS2 (0.45) | MAPTHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL7820966 | 0.75 | PKM (0.41) | MAPTPTGS2ACHE | |
| SCHEMBL16705734 | 0.72 | CYP1A2 (0.47) | FYNHTR2AHTR2CHTR2BPTGS2 | |
| SCHEMBL7036251 | 0.72 | NFKB1 (0.54) | FYNMAPTHTR2AHTR2CHTR2B | |
| SCHEMBL7040275 | 0.67 | ALDH1A1 (0.48) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL2744767 | 0.67 | ALDH1A1 (0.50) | MAPTL3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL28586196 | 0.66 | SMN1; SMN2 (0.65) | MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL11233982 | 0.66 | PTGS2 (0.45) | MAPTHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL8481616 | 0.66 | TPMT (0.59) | L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574510-B1 | 2,4-DIARYL-1,3-DITHIOLANES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CT FOR INNOVATIVE TECHNOLOGY (US) | 2001-09-05 | — | — | EP | disclosed |
| US-5639782-A | ANTIINFLAMMATORY AGENT; ANTIALLERGENS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0574510-A4 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | INNOVATIVE TECH CENTER (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0574510-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015294-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1992-09-17 | — | — | WO | disclosed |