Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831500 | 0.93 | TUBB4A (0.48) | F2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7827676 | 0.92 | ALDH1A1 (0.47) | F2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7827833 | 0.86 | KDM4E (0.56) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7830946 | 0.86 | TP53 (0.48) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7819234 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7833669 | 0.78 | GSK3B (0.57) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7831493 | 0.77 | CDK2 (0.54) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7819220 | 0.77 | KDM4E (0.58) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7829401 | 0.77 | AURKA (0.40) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7819484 | 0.75 | TP53 (0.59) | MEN1KMT2AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | claimed |
| EP-1149835-A1 | FAT ACCUMULATION INHIBITORY AGENTS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |