Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796116 | 0.86 | SLC22A6 (0.36) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL4952556 | 0.80 | GPR84 (0.41) | SLC22A6CACNA2D1GSTK1CACNB3CACNA1C | |
| SCHEMBL4654992 | 0.78 | ALDH1A1 (0.58) | SLC22A6ALDH1A1LMNATDP1TSHR | |
| SCHEMBL5104868 | 0.78 | ALDH1A1 (0.58) | SLC22A6ALDH1A1LMNATDP1TSHR | |
| SCHEMBL5112958 | 0.78 | ALDH1A1 (0.58) | SLC22A6ALDH1A1LMNATDP1TSHR | |
| SCHEMBL5857074 | 0.78 | — | — | |
| SCHEMBL317762 | 0.77 | LMNA (0.61) | SLC22A6ALDH1A1LMNATDP1TSHR | |
| SCHEMBL7527544 | 0.77 | LMNA (0.35) | SLC22A6CACNA2D1GSTK1CACNB3CACNA1C | |
| SCHEMBL3896270 | 0.77 | SLC22A6 (0.39) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL6575970 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101910116-B | Method for production of (2E,6Z,8E)-N-isobutyl-2,6,8-decatrienamide (spilanthol), and foods, beverages, cosmetics and pharmaceutical preparations each comprising the compound | TAKASAGO PERFUMERY CO LTD | 2013-06-19 | — | — | CN | disclosed |
| CN-101910116-A | Method for production of (2E,6Z,8E)-N-isobutyl-2,6,8-decatrienamide (spilanthol), and foods, beverages, cosmetics and pharmaceutical preparations each comprising the compound | TAKASAGO PERFUMERY CO LTD | 2010-12-08 | — | — | CN | disclosed |
| EP-0652871-B1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2001-10-17 | — | — | EP | disclosed |
| US-5618812-A | GASTRIN ANTAGONISTS; GASTROINTESTINAL DISORDERS | MERCK SHARP & DOHME, LTD. (GB) | 1997-04-08 | — | — | US | disclosed |
| US-5438055-A | Antiarrhythmic benzodiazepines | MERCK & CO., INC. (US) | 1995-08-01 | — | — | US | disclosed |
| WO-1995014473-A1 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| EP-0652871-A1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994003437-A1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |