Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 5/20 | 0.39 |
| ▸ | IGF1R | P08069 | 3/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819968 | 0.91 | KMT2A (0.39) | ALDH1A1MAPTTDP1RECQLSMN1; SMN2 | |
| SCHEMBL7821934 | 0.81 | PDE9A (0.33) | PDE9ACAMK2DNPEPPS | |
| SCHEMBL7822940 | 0.81 | CAMK2D (0.38) | MAPTTDP1PDE9ACAMK2DNPEPPS | |
| SCHEMBL7812544 | 0.80 | NPEPPS (0.38) | ALDH1A1PDE9ACAMK2DGAANPEPPS | |
| SCHEMBL7819587 | 0.79 | MAPT (0.37) | ALDH1A1MAPTNPC1GAASMN1; SMN2 | |
| Acetic Acid SCHEMBL7840658 | 0.78 | NPEPPS (0.33) | PDE9ACAMK2DNPEPPS | |
| Trifluoroacetic Acid SCHEMBL7838986 | 0.76 | SSTR4 (0.33) | PDE9A | |
| SCHEMBL7826410 | 0.76 | CAMK2D (0.33) | PDE9ACAMK2D | |
| SCHEMBL7820462 | 0.75 | CAMK2D (0.34) | PDE9ACAMK2DNPEPPS | |
| SCHEMBL7827359 | 0.74 | CAMK2D (0.40) | MAPTTDP1PDE9ACAMK2DNPEPPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |