SCHEMBL7823315

SCHEMBL7823315

O=C(O)C1C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
MAPT P10636 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HTT P42858 2/20 0.42
ALDH1A1 P00352 3/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NR4A2 P43354 2/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
OPRK1 P41145 1/20 0.38
TSHR P16473 2/20 0.38
ABCC4 O15439 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8188595 0.87 CYP1A2 (0.54) LMNATSHRGAAKDM4EALOX15
SCHEMBL8190432 0.82 OPRK1 (0.49) LMNAMAPTMEN1KMT2AHTT
SCHEMBL2918529 0.81 LMNA (0.52) LMNAMAPTHTTSMN1; SMN2TSHR
SCHEMBL8713659 0.81 TSHR (0.49) LMNAMAPTNPSR1ALDH1A1NPC1
SCHEMBL15381249 0.80 LMNA (0.61) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL14957913 0.78 TPMT (0.44) LMNA
SCHEMBL14957911 0.77 ACMSD (0.50) LMNACES2CES1
SCHEMBL30464216 0.75 LMNA (0.50) LMNAALDH1A1GAA
SCHEMBL11785796 0.73 CA1 (0.50) NPC1RAB9ASMN1; SMN2NR4A2CES2
SCHEMBL11527593 0.72 EDNRA (0.50) LMNAMEN1KMT2ANPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580463-B2 Reactants for optical data storage media and methods for use GENERAL ELECTRIC COMPANY (US) 2013-11-12 US claimed
US-20130128712-A1 REACTANTS FOR OPTICAL DATA STORAGE MEDIA AND METHODS FOR USE GENERAL ELECTRIC COMPANY (US) 2013-05-23 US claimed
WO-1998049141-A1 KAPPA OPIOID AGONISTS WARNER-LAMBERT COMPANY (US) 1998-11-05 WO claimed
US-4315978-A Solid-state color imaging device having a color filter array using a photocrosslinkable barrier EASTMAN KODAK COMPANY (US) 1982-02-16 US claimed
EP-0035886-A2 Solid-state imaging device having a color filter array and methods of preparing same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-09-16 EP claimed
EP-2595155-B1 REVERSE SATURABLE ABSORBTION SENSITIZERS FOR OPTICAL DATA STORAGE MEDIA AND METHODS FOR USE. GEN ELECTRIC (US) 2015-09-16 EP disclosed
US-8580464-B2 Reverse saturable absorbtion sensitizers for optical data storage media and methods for use GENERAL ELECTRIC COMPANY (US) 2013-11-12 US disclosed
US-8580463-B2 Reactants for optical data storage media and methods for use GENERAL ELECTRIC COMPANY (US) 2013-11-12 US disclosed
US-8580463-B2 Reactants for optical data storage media and methods for use GENERAL ELECTRIC COMPANY (US) 2013-11-12 US disclosed
US-8580463-B2 Reactants for optical data storage media and methods for use GENERAL ELECTRIC COMPANY (US) 2013-11-12 US disclosed
US-20130128712-A1 REACTANTS FOR OPTICAL DATA STORAGE MEDIA AND METHODS FOR USE GENERAL ELECTRIC COMPANY (US) 2013-05-23 US disclosed
US-20130128712-A1 REACTANTS FOR OPTICAL DATA STORAGE MEDIA AND METHODS FOR USE GENERAL ELECTRIC COMPANY (US) 2013-05-23 US disclosed
US-6020519-A Diphenyl-cyclopropenes as selective K-agonists WARNER-LAMBERT COMPANY (US) 2000-02-01 US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5968968-A Diphenyl-cyclopropenes as selective K-agonists WARNER-LAMBERT COMPANY (US) 1999-10-19 US disclosed
WO-1998049141-A1 KAPPA OPIOID AGONISTS WARNER-LAMBERT COMPANY (US) 1998-11-05 WO disclosed
WO-1998003491-A1 DIPHENYL-CYCLOPROPENES AS SELECTIVE K-AGONISTS WARNER-LAMBERT COMPANY (US) 1998-01-29 WO disclosed
US-4357415-A Method of making a solid-state color imaging device having a color filter array using a photocrosslinkable barrier EASTMAN KODAK COMPANY (US) 1982-11-02 US disclosed
US-4315978-A Solid-state color imaging device having a color filter array using a photocrosslinkable barrier EASTMAN KODAK COMPANY (US) 1982-02-16 US disclosed
EP-0035886-A2 Solid-state imaging device having a color filter array and methods of preparing same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-09-16 EP disclosed