Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100657 | 0.90 | HTR1A (0.58) | KMT2AHTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL11523072 | 0.81 | HTR1A (0.57) | KMT2AHTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL9148324 | 0.80 | L3MBTL1 (0.73) | KMT2AL3MBTL1NPC1RAB9ACES2 | |
| SCHEMBL10596068 | 0.78 | AKR1C3 (0.49) | KMT2AAKR1C3AKR1C2HTR1ASMN1; SMN2 | |
| SCHEMBL6169730 | 0.77 | CES2 (0.56) | KMT2AHTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL11203155 | 0.77 | CES2 (0.56) | KMT2AHTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL7797487 | 0.76 | KMO (0.57) | KMT2AHTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL7797484 | 0.76 | KMO (0.57) | KMT2AHTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL7801993 | 0.76 | KMO (0.57) | KMT2AHTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL1980988 | 0.75 | CES2 (0.61) | KMT2AHTR1AADRA2ADRD1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |