Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942208 | 0.86 | TSHR (0.47) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 | |
| SCHEMBL27546397 | 0.81 | ESPL1 (0.40) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 | |
| SCHEMBL5865009 | 0.81 | HTT (0.44) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 | |
| SCHEMBL15452634 | 0.79 | CYP19A1 (0.46) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 | |
| SCHEMBL20553784 | 0.78 | CYP19A1 (0.50) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 | |
| SCHEMBL1424323 | 0.74 | TSHR (0.45) | ALDH1A1CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL212845 | 0.73 | CYP19A1 (0.81) | CYP19A1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL1026447 | 0.72 | CYP19A1 (0.62) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 | |
| SCHEMBL219410 | 0.72 | CYP19A1 (0.55) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 | |
| SCHEMBL589656 | 0.71 | TSHR (0.56) | CYP19A1ALDH1A1CYP3A4TSHRESPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903048-A | Synthesis method of 4-bromo-2, 6-diaminopyridine | 苏州艾缇克药物化学有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-9537105-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-01-03 | — | — | US | disclosed |
| CN-103249732-B | The bacterial topoisomerase II of suppression 2-ethyl carbamyl amino-1,3-benzothiazole-5-base | 生物区欧洲有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-9181234-B2 | Antibacterial compounds | BIOTA EUROPE LTD. (GB) | 2015-11-10 | — | — | US | disclosed |
| US-9181234-B2 | Antibacterial compounds | BIOTA EUROPE LTD. (GB) | 2015-11-10 | — | — | US | disclosed |
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-9126970-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-9040172-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-05-26 | — | — | US | disclosed |
| US-8841460-B2 | Tunable phenylacetylene hosts | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2014-09-23 | — | — | US | disclosed |
| US-20140031559-A1 | TUNABLE PHENYLACETYLENE HOSTS | State of Oregon, acting by and through the State Board of Higher Education on Behalf of University (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2007093901-A1 | 3 -DEAZAPURINE DERIVATIVES AS TLR7 MODULATORS | PFIZER LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |
| US-20060194782-A1 | Pharmacologically active imidazo[4,5-c] pyridines | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
| EP-1670795-A1 | PHARMACOLOGICALLY ACTIVE IMIDAZO 4,5-C PYRIDINES | ALTANA Pharma AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005026164-A1 | PHARMACOLOGICALLY ACTIVE IMIDAZO[4,5-C]PYRIDINES | ALTANA PHARMA AG (DE) | 2005-03-24 | — | — | WO | disclosed |
| WO-2004030029-A2 | CONDUCTING POLYMER DEVICES FOR INTER-CONVERTING LIGHT AND ELECTRICITY | RISØ NATIONAL LABORATORY (DK) | 2004-04-08 | — | — | WO | disclosed |
| EP-0819118-B1 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY (AU) | 2002-09-18 | — | — | EP | disclosed |
| US-5929082-A | SULFONYL(THIO)UREA AND SULFONYLGUANIDINE COMPOUNDS; TREATMENT OF DIABETES, CARDIAC ARRHYTHMIAS, ISCHEMIA, HYPOXIC CARDIOVASCUALR DISORDERS AND CANCER | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 1999-07-27 | — | — | US | disclosed |
| EP-0819118-A4 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY (AU) | 1998-04-29 | — | — | EP | disclosed |
| EP-0819118-A1 | POTASSIUM ION CHANNEL BLOCKERS | Polychip Pharmaceuticals Pty. Ltd. (AU) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996030341-A1 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY. LTD. (AU) | 1996-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO2B1, SLCO1B3, SLCO4C1 | CYP19A1 1789/4885ALDH1A1 1226/4885CYP3A4 319/4885 |
| US-20140031559-A1 | TUNABLE PHENYLACETYLENE HOSTS | NAA10, OR10J3, CBR3 | CYP19A1 3409/4885ALDH1A1 4677/4885CYP3A4 3698/4885 |
| US-20060194782-A1 | Pharmacologically active imidazo[4,5-c] pyridines | GIPR, VIP, PGC | CYP19A1 1914/4885ALDH1A1 935/4885CYP3A4 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.