Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782398 | 0.93 | CA14 (0.32) | MEN1NPC1RAB9AKMT2ATDP1 | |
| SCHEMBL1742306 | 0.83 | AKT1 (0.38) | TDP1CASRTSHR | |
| SCHEMBL4918504 | 0.80 | CA14 (0.37) | CASR | |
| SCHEMBL782293 | 0.79 | CTSS (0.35) | MEN1KMT2A | |
| SCHEMBL1722554 | 0.79 | TSHR (0.47) | MEN1NPC1RAB9AKMT2ATDP1 | |
| SCHEMBL13254363 | 0.79 | PHF8 (0.34) | — | |
| SCHEMBL9893327 | 0.79 | PHF8 (0.39) | TDP1CASRTSHR | |
| SCHEMBL1966612 | 0.77 | ALDH1A1 (0.37) | RAB9AKMT2ATDP1 | |
| SCHEMBL6534709 | 0.76 | HDAC6 (0.33) | TDP1CASR | |
| SCHEMBL9945620 | 0.75 | PHF8 (0.39) | TDP1CASRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | ORC3, TXN, PROC | MEN1 3244/4885NPC1 4300/4885RAB9A 3320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.