Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826306 | 0.86 | GAA (0.45) | GPR35MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL8800344 | 0.85 | EYA3 (0.44) | GPR35RAB9ALMNAPKMMEN1 | |
| SCHEMBL7831814 | 0.84 | RAB9A (0.42) | GPR35MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL7823933 | 0.84 | MAPT (0.48) | GPR35MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL8341922 | 0.83 | GPR35 (0.42) | GPR35MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL7826421 | 0.82 | ACHE (0.42) | GPR35MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL7817291 | 0.82 | RAB9A (0.41) | MAPTRAB9AALDH1A1LMNANPSR1 | |
| SCHEMBL7826424 | 0.82 | ACHE (0.42) | GPR35MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL7824655 | 0.81 | KMT2A (0.44) | GPR35MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL7816264 | 0.81 | TYK2 (0.47) | MAPTRAB9AALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |