Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818117 | 0.82 | SIRT2 (0.44) | SIRT2 | |
| SCHEMBL5751606 | 0.78 | SIRT2 (0.35) | SIRT2 | |
| SCHEMBL5748437 | 0.78 | SIRT2 (0.36) | SIRT2 | |
| SCHEMBL7831405 | 0.78 | SIRT2 (0.35) | SIRT2NMBRALOX5AP | |
| SCHEMBL7844409 | 0.77 | ALOX5 (0.52) | SIRT2 | |
| SCHEMBL7597443 | 0.74 | MAOA (0.39) | SIRT2 | |
| SCHEMBL7594682 | 0.74 | SIRT2 (0.41) | SIRT2ALOX5AP | |
| SCHEMBL6674214 | 0.71 | KCNH2 (0.46) | SIRT2CYSLTR2CYSLTR1 | |
| SCHEMBL4855420 | 0.71 | SIRT2 (0.48) | SIRT2 | |
| SCHEMBL14289994 | 0.69 | SIRT2 (0.46) | SIRT2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073640-A1 | NAPHTHALENE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054309-A1 | NAPHTHALENE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |