Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844409 | 0.81 | ALOX5 (0.52) | MAOAMAOBMRGPRX4SIRT2CA12 | |
| SCHEMBL7818117 | 0.80 | SIRT2 (0.44) | MAOBSIRT2 | |
| SCHEMBL7594682 | 0.77 | SIRT2 (0.41) | SIRT2CA12CA9 | |
| SCHEMBL6674214 | 0.75 | KCNH2 (0.46) | SIRT2 | |
| SCHEMBL4027506 | 0.75 | ENPP2 (0.31) | SIRT2 | |
| SCHEMBL7828102 | 0.74 | SIRT2 (0.40) | SIRT2 | |
| SCHEMBL4031880 | 0.74 | CTNNB1 (0.34) | SIRT2 | |
| SCHEMBL7831405 | 0.72 | SIRT2 (0.35) | SIRT2 | |
| SCHEMBL5203299 | 0.72 | MAOB (0.50) | MAOBSIRT2 | |
| SCHEMBL7384162 | 0.70 | ALDH1A1 (0.53) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222174-A1 | IMIDAZOL-4-YLMETHANOLS USED AS INHIBITORS OF STEROID C17-20 LYASE | Takeda Chemical Industries, Ltd. (JP) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001030762-A1 | IMIDAZOL-4-YLMETHANOLS USE AS INHIBITORS OF STEROID C17-20 LYASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |