Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264847 | 0.85 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9328262 | 0.83 | ADORA3 (0.67) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9328920 | 0.82 | ADORA2B (0.66) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9427973 | 0.82 | ADORA2A (0.72) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9327033 | 0.81 | ADORA3 (0.51) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9325959 | 0.81 | ADORA3 (0.48) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL5428722 | 0.80 | ADORA2A (1.00) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9327336 | 0.80 | ADORA3 (0.69) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9325713 | 0.79 | ADORA3 (0.46) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9327392 | 0.79 | ADORA3 (0.67) | ADORA3ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667349-B1 | DEPRESSION REMEDY | KYOWA HAKKO KOGYO KK (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0667349-A1 | DEPRESSION REMEDY | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1995-08-16 | — | — | EP | disclosed |