Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327033 | 0.86 | ADORA3 (0.51) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9328945 | 0.84 | ADORA3 (0.64) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL7828518 | 0.81 | ADORA3 (0.73) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9325713 | 0.75 | ADORA3 (0.46) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9328936 | 0.73 | ADORA3 (0.42) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9327287 | 0.70 | ADORA3 (0.65) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL23840696 | 0.66 | ADORA3 (0.64) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9328262 | 0.65 | ADORA3 (0.67) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9264847 | 0.65 | ADORA3 (1.00) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL9328920 | 0.64 | ADORA2B (0.66) | ADORA3ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356894-A | Adenosine antagonists | SYNGENTA LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0459702-A1 | Azole Derivatives | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |