Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058257 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL9516092 | 0.84 | L3MBTL1 (0.45) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL7047572 | 0.83 | PDCD1 (0.49) | CD274PDCD1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9960478 | 0.83 | ACLY (0.46) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL28321273 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL28968075 | 0.82 | FFAR4 (0.43) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL27717755 | 0.79 | SLC6A3 (0.55) | CD274PDCD1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL29018628 | 0.79 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL1750794 | 0.78 | POLB (0.53) | KDM4EALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL28422371 | 0.78 | PPARG (0.44) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |