Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058257 | 0.85 | KDM4E (0.53) | KDM4EPKMALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL9516092 | 0.83 | L3MBTL1 (0.45) | ACLYKDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL7828889 | 0.83 | CD274 (0.47) | ACLYKDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL28321273 | 0.81 | KDM4E (0.48) | ACLYKDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL28968075 | 0.81 | FFAR4 (0.43) | KDM4EPKMALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL31567693 | 0.79 | ACLY (0.42) | ACLYKDM4EALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL1261700 | 0.79 | ACLY (0.42) | ACLYKDM4EALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL29018628 | 0.77 | KDM4E (0.40) | ACLYKDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL29231445 | 0.76 | ESR1 (0.42) | ACLYKDM4EALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL5965055 | 0.76 | ACHE (0.40) | ACLYKDM4EPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084978-A1 | (R)-2-(3-FLUORO-4-PHENYLPHENYL)PROPIONIC ACID FOR USE IN THE TREATMENT OF SKIN DISEASES | GALENPHARMA GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |