SCHEMBL9516092

SCHEMBL9516092

CCC(=O)Oc1cccc(-c2ccccc2)c1OC(=O)CC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
KDM4E B2RXH2 7/20 0.44
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 2/20 0.43
MAPK1 P28482 2/20 0.43
ELANE P08246 1/20 0.43
PKM P14618 1/20 0.42
ACLY P53396 1/20 0.42
MAPT P10636 2/20 0.41
USP2 O75604 1/20 0.41
HTT P42858 1/20 0.41
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
BACE1 P56817 1/20 0.40
HTR7 P34969 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28968075 0.91 FFAR4 (0.43) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL2058257 0.87 KDM4E (0.53) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL11223708 0.84 L3MBTL1 (0.45) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL7828889 0.84 CD274 (0.47) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL14315097 0.83 POLM (0.58) KDM4EMEN1RECQLKMT2A
SCHEMBL9960478 0.83 ACLY (0.46) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL7385921 0.83 ALDH1A1 (0.43) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL28321273 0.82 KDM4E (0.48) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL8676657 0.79 MAPK1 (0.60) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL29018628 0.79 KDM4E (0.40) L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0314173-B1 Thermoplastic wholly aromatic polyimide esters and process for producing the same IDEMITSU PETROCHEMICAL CO (JP) 1993-12-29 EP disclosed
US-4874836-A COMPRISING MONOMERS OF P-HYDROXYBENZOIC ACID, A HYROXY-AND/OR CARBOXY-CONAINING 2-PHENYLISOINDOLINE-1,3-DIONE, HYDROQUINONE OR P,P*-DIHYDROXYBIPHENYL AND ISO- OR TEREPHTHALIC ACID; DIMENSIONAL STABILITY IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1989-10-17 US disclosed
EP-0314173-A2 Thermoplastic wholly aromatic polyimide esters and process for producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1989-05-03 EP disclosed