Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828179 | 0.84 | AKR1C3 (0.53) | AKR1C3MEN1KMT2APTGER4ERCC5 | |
| SCHEMBL7829626 | 0.81 | AKR1C3 (0.49) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL7827319 | 0.78 | ALOX15 (0.48) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL27481611 | 0.78 | MAPT (0.52) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL7824962 | 0.78 | AKR1C3 (0.51) | AKR1C3MEN1KMT2AL3MBTL1CYP19A1 | |
| SCHEMBL7816139 | 0.77 | ALOX15 (0.51) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL7830775 | 0.77 | UCHL1 (0.53) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22608343 | 0.77 | CYP19A1 (0.56) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL7826324 | 0.76 | MAPT (0.43) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL21296940 | 0.75 | MEN1 (0.54) | AKR1C3MEN1KMT2AALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |