Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824962 | 0.92 | AKR1C3 (0.51) | AKR1C3PTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7828177 | 0.86 | AKR1C3 (0.47) | AKR1C3MEN1KMT2AALDH1A1PTGER4 | |
| SCHEMBL7829631 | 0.84 | AKR1C3 (0.51) | AKR1C3MEN1KMT2AALDH1A1PTGER4 | |
| SCHEMBL7824961 | 0.80 | CYP19A1 (0.46) | AKR1C3ALDH1A1ADORA3NPC1RAB9A | |
| SCHEMBL1223807 | 0.77 | RAB9A (0.67) | ALDH1A1HTTNPC1RAB9APOLB | |
| SCHEMBL8073566 | 0.76 | CASP3 (0.44) | AKR1C3MEN1KMT2AHTT | |
| SCHEMBL7822920 | 0.76 | AKR1C3 (0.42) | AKR1C3KMT2AALDH1A1PTGER4HTT | |
| SCHEMBL7829626 | 0.74 | AKR1C3 (0.49) | AKR1C3MEN1KMT2AALDH1A1PTGER4 | |
| SCHEMBL11813314 | 0.74 | TP53 (0.68) | ALDH1A1HTTNPC1RAB9APOLB | |
| SCHEMBL7816139 | 0.74 | ALOX15 (0.51) | AKR1C3MEN1KMT2AALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |