Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820993 | 0.90 | SLC10A2 (0.47) | AMY1ATSHRMAPK10SMN1; SMN2NPC1 | |
| SCHEMBL8495782 | 0.86 | SLC10A2 (0.43) | AMY1ATSHRMAPK10SMN1; SMN2NPC1 | |
| SCHEMBL7831401 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1TP53RAB9AKDM4E | |
| SCHEMBL14917022 | 0.77 | PDE5A (0.48) | GUSBSMN1; SMN2NPC1KDM4EHPGD | |
| SCHEMBL7835671 | 0.77 | SLC10A2 (0.36) | SMN1; SMN2RAB9AKDM4EHPGDDHODH | |
| SCHEMBL8491270 | 0.77 | AMY1A (0.39) | AMY1ATSHRMAPK10GUSBSMN1; SMN2 | |
| SCHEMBL8121664 | 0.76 | FABP3 (0.53) | SMN1; SMN2KDM4EHPGDPDE4APDE4B | |
| SCHEMBL8633281 | 0.75 | ALDH1A1 (0.44) | GUSBSMN1; SMN2KDM4EHPGDPDE4A | |
| SCHEMBL7830290 | 0.74 | PDE10A (0.43) | AMY1ATSHRMAPK10GUSBSMN1; SMN2 | |
| SCHEMBL7821021 | 0.73 | MAPK1 (0.53) | TSHRGUSBSMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |