Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792314 | 0.86 | CA12 (0.43) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL9114805 | 0.83 | KDM4E (0.40) | HSD17B10HPGDMAPTKDM4ETDP1 | |
| SCHEMBL7847009 | 0.75 | CA12 (0.39) | HSD17B10HPGDMAPTKDM4ELMNA | |
| SCHEMBL7453451 | 0.75 | MAPT (0.41) | ALOX15MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL7770465 | 0.74 | LMNA (0.35) | HPGDALOX15MAPTKDM4ELMNA | |
| SCHEMBL7844950 | 0.73 | KDM4E (0.36) | HSD17B10MAPTKDM4EL3MBTL1RAB9A | |
| SCHEMBL7768682 | 0.72 | HTT (0.40) | HSD17B10HPGDPTGS2MAPTKDM4E | |
| SCHEMBL7457133 | 0.71 | PTGER4 (0.37) | HPGDMAPTKDM4ELMNACYP3A4 | |
| SCHEMBL7839463 | 0.71 | L3MBTL1 (0.38) | HSD17B10KDM4ETDP1LMNACHRM1 | |
| SCHEMBL8117763 | 0.71 | GRK6 (0.32) | HPGDMAPTKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097155-A2 | PHOTOCHROMIC SIX-MEMBERED HETEROCYCLIC-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002883-A2 | PHOTOCHROMIC SIX-MEMBERED HETEROCYCLIC-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-01-20 | — | — | WO | disclosed |