Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302170 | 0.83 | LMNA (0.36) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10484199 | 0.79 | KMT2A (0.46) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| Ammonia Solution, Strong SCHEMBL10668123 | 0.64 | CYP2D6 (0.33) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6792682 | 0.62 | TSHR (0.45) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28957621 | 0.60 | PGR (0.39) | LMNAL3MBTL1POLBKMT2AHSD17B10 | |
| SCHEMBL17472262 | 0.59 | LMNA (0.36) | LMNAL3MBTL1POLBKMT2ATSHR | |
| SCHEMBL21648164 | 0.59 | — | — | |
| SCHEMBL3492650 | 0.59 | GAA (0.54) | LMNAL3MBTL1POLBCYP2D6CYP2C9 | |
| SCHEMBL12037127 | 0.59 | CYP2D6 (0.56) | LMNAL3MBTL1POLBCYP2D6CYP2C9 | |
| SCHEMBL3490964 | 0.58 | KDM4E (0.38) | LMNAL3MBTL1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |