Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | KCNN3 | Q9UGI6 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.33 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834870 | 0.87 | P2RX7 (0.39) | LOXL2KCNN3KCNN1KCNN2MAPT | |
| SCHEMBL7835023 | 0.87 | LOXL2 (0.49) | LOXL2KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL7833319 | 0.84 | LOXL2 (0.46) | LOXL2KCNN3FFAR1RHEBRAD52 | |
| SCHEMBL7830320 | 0.82 | S1PR4 (0.36) | LOXL2KCNN3MAPTPDE10AP2RX7 | |
| SCHEMBL7830196 | 0.81 | PDE10A (0.40) | LOXL2KCNN3MAPTPDE10A | |
| SCHEMBL7832607 | 0.81 | KCNN3 (0.40) | LOXL2KCNN3FFAR1MMP14KCNN1 | |
| SCHEMBL7829453 | 0.81 | LOXL2 (0.46) | LOXL2KCNN3FFAR1RHEBRAD52 | |
| SCHEMBL7831956 | 0.79 | LOXL2 (0.45) | LOXL2KCNN3FFAR1RHEBRAD52 | |
| SCHEMBL7835475 | 0.79 | LOXL2 (0.47) | LOXL2KCNN3RHEBRAD52CYP1A2 | |
| SCHEMBL7830500 | 0.77 | KDM5A (0.39) | KCNN3KCNN1KCNN2MAPTPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820997-B1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-5985882-A | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0820997-A1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-01-28 | — | — | EP | disclosed |