Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104242 | 0.84 | THRB (0.31) | — | |
| SCHEMBL8310142 | 0.77 | ARG1 (0.32) | — | |
| SCHEMBL3037355 | 0.77 | MEN1 (0.30) | — | |
| SCHEMBL14582634 | 0.74 | CA1 (0.32) | — | |
| SCHEMBL8316272 | 0.74 | — | — | |
| SCHEMBL8313149 | 0.74 | CA2 (0.31) | — | |
| Sulfuric Acid SCHEMBL30118976 | 0.74 | CA5A (0.35) | TP53 | |
| SCHEMBL13103990 | 0.73 | — | — | |
| SCHEMBL14582615 | 0.73 | CA1 (0.31) | — | |
| SCHEMBL8311112 | 0.73 | CA2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781283-B1 | TRIAZOLOPYRIDAZINES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-06-06 | — | — | EP | disclosed |
| EP-0562439-B1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| CN-1158130-A | Triazolopyridazines, their preparation and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-08-27 | — | — | CN | disclosed |
| EP-0781283-A1 | TRIAZOLOPYRIDAZINES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008496-A1 | TRIAZOLOPYRIDAZINES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |
| US-5482939-A | ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389633-A | ANTIASTHMATIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0562439-A1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5155108-A | Imidazopyridazines and use as antiasthmatic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0440119-A1 | Imidazopyridazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-07 | — | — | EP | disclosed |