SCHEMBL7832015

SCHEMBL7832015

CCOC(=O)N(C)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.33
LMNA P02545 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PPOX P50336 3/20 0.32
BAZ2B Q9UIF8 1/20 0.31
BAZ2A Q9UIF9 1/20 0.31
TSHR P16473 1/20 0.31
KAT2B Q92831 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10697219 0.86 DHODH (0.31)
SCHEMBL27674184 0.82 GRM4 (0.31) PLA2G7
SCHEMBL6336900 0.82 BAZ2B (0.46) LMNABAZ2BBAZ2A
SCHEMBL10575943 0.82 PPOX (0.38) MEN1KMT2APPOX
SCHEMBL7832776 0.82 PLA2G7 (0.35) PLA2G7PPOXKAT2B
SCHEMBL7833799 0.80 KMT2A (0.38) KMT2A
SCHEMBL10574869 0.79 L3MBTL1 (0.30) PPOX
SCHEMBL10577739 0.79 MAPT (0.34) PPOXTSHR
SCHEMBL10574794 0.78 PPOX (0.36) MEN1KMT2APPOXBAZ2BBAZ2A
SCHEMBL7951761 0.78 PKM (0.35) PPOXBAZ2BBAZ2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563384-B1 URACIL DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-10-04 EP disclosed
US-5356863-A Herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed
EP-0563384-A1 URACIL DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-10-06 EP disclosed