SCHEMBL7832776

SCHEMBL7832776

CCOC(=O)CN(c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl)S(=O)(=O)CC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.35
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PPOX P50336 1/20 0.33
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32
KAT2B Q92831 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7833965 0.84 MAPT (0.52) MAPTKDM4E
SCHEMBL7832015 0.82 PLA2G7 (0.33) PLA2G7PPOXKAT2B
SCHEMBL6336900 0.78 BAZ2B (0.46) MAPTKDM4E
SCHEMBL9679387 0.76
SCHEMBL7950037 0.76
SCHEMBL27674184 0.76 GRM4 (0.31) PLA2G7
SCHEMBL7955672 0.76 ALDH1A1 (0.32) MAPTKDM4E
SCHEMBL7951626 0.76 KMT2A (0.31)
SCHEMBL10697219 0.76 DHODH (0.31)
SCHEMBL7833799 0.75 KMT2A (0.38) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563384-B1 URACIL DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-10-04 EP disclosed
US-5356863-A Herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed
EP-0563384-A1 URACIL DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-10-06 EP disclosed