Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829657 | 0.85 | SMN1; SMN2 (0.51) | MAPK1MAPTKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL7831499 | 0.82 | HDAC1 (0.51) | MAPTALOX5LMNA | |
| SCHEMBL6642195 | 0.75 | L3MBTL1 (0.69) | L3MBTL1MAPK1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7835269 | 0.74 | HDAC1 (0.46) | GAAALDH1A1 | |
| SCHEMBL9811164 | 0.74 | MAPT (0.53) | L3MBTL1MAPK1MAPTKDM4EMEN1 | |
| Bromide SCHEMBL1362177 | 0.73 | L3MBTL1 (0.62) | L3MBTL1MAPK1MAPTKDM4ERAB9A | |
| SCHEMBL10653229 | 0.73 | RAB9A (0.58) | L3MBTL1MAPK1MAPTKDM4ERAB9A | |
| SCHEMBL7820980 | 0.73 | TNF (0.46) | L3MBTL1MAPTKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9705564 | 0.72 | CYP3A4 (0.49) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8035390 | 0.72 | L3MBTL1 (0.45) | L3MBTL1MAPK1MAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |