Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 3/20 | 0.45 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310152 | 0.92 | FERMT2 (0.57) | HRH3FERMT2HSP90AA1HSP90AB1NOS3 | |
| SCHEMBL29404716 | 0.83 | CCR1 (0.48) | FERMT2NOS3NOS1NOS2HTR1A | |
| SCHEMBL6092097 | 0.82 | ROCK2 (0.51) | NOS3NOS1NOS2HTR1AADRA1D | |
| SCHEMBL7833347 | 0.80 | KARS1 (0.64) | HRH3FERMT2NOS2KARS1STK17A | |
| SCHEMBL10151327 | 0.77 | APP (0.45) | HRH3FERMT2HSP90AA1HSP90AB1HTR1A | |
| SCHEMBL15286744 | 0.77 | FERMT2 (0.43) | HRH3FERMT2NOS1NOS2KARS1 | |
| SCHEMBL11465581 | 0.76 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1NOS3NOS1NOS2 | |
| SCHEMBL2570584 | 0.75 | NOS3 (0.57) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL30001628 | 0.75 | NOS3 (0.57) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL17700550 | 0.75 | HRH4 (0.50) | NOS3NOS1NOS2CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124821-A1 | COMPOUNDS | AstraZeneca AB (SE) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000027842-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2000-05-18 | — | — | WO | disclosed |