Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 5/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836324 | 0.85 | KAT6A (0.46) | SOS1PGRKMT2A | |
| SCHEMBL7211 | 0.82 | HTR6 (0.46) | LMNAHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL5653955 | 0.80 | F2 (0.37) | LMNAHTTKMT2AALDH1A1 | |
| SCHEMBL7824474 | 0.79 | CA12 (0.50) | SMN1; SMN2CA1CA2CA9MMP1 | |
| SCHEMBL15048693 | 0.79 | TTR (0.43) | LMNAHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL1945898 | 0.78 | F2 (0.56) | HTTCA1CA2CA9MMP1 | |
| SCHEMBL27170943 | 0.78 | HTT (0.68) | SOS1LMNAHTTSMN1; SMN2CA1 | |
| SCHEMBL10830968 | 0.76 | CASP1 (0.43) | SOS1LMNAHTTCA1CA2 | |
| SCHEMBL6123058 | 0.74 | HTT (0.81) | SOS1LMNAHTTSMN1; SMN2CA1 | |
| SCHEMBL146566 | 0.74 | HTT (0.81) | SOS1LMNAHTTSMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |