Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832776 | 0.84 | PLA2G7 (0.35) | MAPTKDM4E | |
| SCHEMBL7955672 | 0.83 | ALDH1A1 (0.32) | MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL9679387 | 0.82 | — | — | |
| SCHEMBL7951626 | 0.81 | KMT2A (0.31) | KMT2A | |
| SCHEMBL25480715 | 0.79 | KAT2B (0.36) | — | |
| SCHEMBL8700628 | 0.78 | — | — | |
| SCHEMBL27674206 | 0.78 | KAT2B (0.37) | MAPTHSD17B10 | |
| SCHEMBL27674184 | 0.77 | GRM4 (0.31) | — | |
| SCHEMBL5655918 | 0.77 | DHODH (0.36) | — | |
| SCHEMBL10697219 | 0.77 | DHODH (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563384-B1 | URACIL DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-5356863-A | Herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0563384-A1 | URACIL DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |