⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680350 | 0.91 | — | — | |
| SCHEMBL7951626 | 0.90 | KMT2A (0.31) | — | |
| SCHEMBL27674184 | 0.86 | GRM4 (0.31) | — | |
| SCHEMBL7955672 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL6697540 | 0.84 | BCAT2 (0.35) | — | |
| SCHEMBL10695874 | 0.83 | BCAT1 (0.34) | — | |
| SCHEMBL10695876 | 0.83 | BCAT1 (0.34) | — | |
| SCHEMBL10695716 | 0.83 | HSD11B1 (0.32) | — | |
| SCHEMBL7833965 | 0.82 | MAPT (0.52) | — | |
| SCHEMBL10697219 | 0.81 | DHODH (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5154755-A | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0489480-A1 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-06-10 | — | — | EP | disclosed |
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |