SCHEMBL7955672

SCHEMBL7955672

C=CCN(c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl)S(C)(=O)=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679387 0.84
SCHEMBL7951626 0.83 KMT2A (0.31)
SCHEMBL10695783 0.83
SCHEMBL7833965 0.83 MAPT (0.52) ALDH1A1TSHRKDM4EMAPT
SCHEMBL27674184 0.79 GRM4 (0.31)
SCHEMBL7950037 0.78
SCHEMBL10695876 0.77 BCAT1 (0.34)
SCHEMBL10695874 0.77 BCAT1 (0.34)
SCHEMBL10695716 0.77 HSD11B1 (0.32)
SCHEMBL7832776 0.76 PLA2G7 (0.35) KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207830-B1 REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE SYNGENTA CROP PROTECTION, INC. 2001-03-27 US claimed
EP-0831091-A2 Process for the production of 3-aryl-uracils Novartis AG (CH) 1998-03-25 EP claimed
US-6207830-B1 REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE SYNGENTA CROP PROTECTION, INC. 2001-03-27 US disclosed
EP-0831091-A2 Process for the production of 3-aryl-uracils Novartis AG (CH) 1998-03-25 EP disclosed