Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822006 | 0.87 | LGMN (0.44) | ADORA3ADORA2BTP53PKMRAB9A | |
| SCHEMBL7830852 | 0.84 | CCNB2 (0.43) | ADORA3ADORA2BSMN1; SMN2CCNB2CDK1 | |
| SCHEMBL7835021 | 0.83 | MAPT (0.41) | ADORA3ADORA2BPKMRAB9ASMN1; SMN2 | |
| SCHEMBL7847076 | 0.83 | ADORA3 (0.41) | ADORA3ADORA2BPKMRAB9ASMN1; SMN2 | |
| SCHEMBL7844326 | 0.82 | KDM4E (0.41) | ADORA3ADORA2BTP53PKMRAB9A | |
| SCHEMBL11196780 | 0.76 | KDM4E (0.49) | PKMSMN1; SMN2CCNB2CDK1CCNB1 | |
| SCHEMBL7830685 | 0.76 | KMT2A (0.58) | SMN1; SMN2CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL7831973 | 0.76 | KMT2A (0.55) | SMN1; SMN2CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL7821723 | 0.76 | LMNA (0.50) | TP53SMN1; SMN2CCNB2CDK1CCNB1 | |
| SCHEMBL7830310 | 0.75 | MEN1 (0.48) | ADORA3ADORA2BPKMRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5840732-A | ANTIDIABETIC AGENTS, AUTOIMMUNE DISEASES OR IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 1998-11-24 | — | — | US | disclosed |