Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974165 | 0.89 | OPRL1 (0.42) | MCHR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7872456 | 0.89 | OPRL1 (0.42) | MCHR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8508323 | 0.89 | OPRL1 (0.42) | MCHR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6974169 | 0.89 | OPRL1 (0.42) | MCHR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6979034 | 0.89 | OPRL1 (0.42) | MCHR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6982502 | 0.78 | HRH3 (0.34) | MCHR1HRH3 | |
| SCHEMBL6982504 | 0.78 | HRH3 (0.34) | MCHR1HRH3 | |
| SCHEMBL8475345 | 0.78 | HRH3 (0.34) | MCHR1HRH3 | |
| SCHEMBL6981689 | 0.77 | SLC6A9 (0.36) | MCHR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6979254 | 0.77 | SLC6A2 (0.41) | OPRM1OPRD1OPRK1OPRL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010009921-A1 | Less tendency to cause drug dependency, analgesic, anesthetic, anti-inflammatory or neuroprotective agent; subtype of opoid receptor | ITO FUMITAKA (JP) | 2001-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010009921-A1 | Less tendency to cause drug dependency, analgesic, anesthetic, anti-inflammatory or neuroprotective agent; subtype of opoid receptor | OPRL1, OPRD1, OPRK1 | MCHR1 280/4885OPRM1 4/4885OPRD1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.