Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 12/20 | 0.42 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825812 | 0.91 | TP53 (0.39) | GPR132CMKLR2CMKLR1ALDH1A1TP53 | |
| SCHEMBL7825718 | 0.90 | TP53 (0.47) | ALDH1A1TP53 | |
| SCHEMBL7832625 | 0.89 | TP53 (0.41) | GPR132CMKLR2CMKLR1ALDH1A1TP53 | |
| SCHEMBL6776672 | 0.89 | GPR132 (0.52) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL6776531 | 0.88 | GPR132 (0.47) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL7341105 | 0.87 | CTSL (0.46) | ALDH1A1TP53 | |
| SCHEMBL7340855 | 0.87 | TSHR (0.45) | GPR132CMKLR2CMKLR1ALDH1A1TP53 | |
| SCHEMBL7341748 | 0.87 | TACR1 (0.41) | ALDH1A1TP53 | |
| SCHEMBL7344058 | 0.86 | GLA (0.41) | TP53MAPT | |
| SCHEMBL6773680 | 0.86 | ALDH1A1 (0.44) | GPR132CMKLR2CMKLR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | claimed |
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | disclosed |