Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 7/20 | 0.50 |
| ▸ | FLT4 | P35916 | 7/20 | 0.50 |
| ▸ | KDR | P35968 | 7/20 | 0.50 |
| ▸ | EGFR | P00533 | 7/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838561 | 0.94 | FLT1 (0.54) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL7833152 | 0.85 | FLT1 (0.50) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL7835295 | 0.84 | KDM4E (0.46) | EGFRERBB2LMNASMN1; SMN2MEN1 | |
| SCHEMBL11223447 | 0.81 | EGFR (0.53) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL7837784 | 0.81 | LMNA (0.51) | L3MBTL1ALDH1A1LMNACYP3A4MMP2 | |
| SCHEMBL11537066 | 0.76 | GAA (0.44) | EGFRALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11537067 | 0.76 | GAA (0.44) | EGFRALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL25297441 | 0.73 | ALDH1A1 (0.57) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL3693620 | 0.72 | FLT1 (0.67) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL10538089 | 0.72 | NPSR1 (0.46) | L3MBTL1ALDH1A1LMNACYP3A4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |