Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 11/20 | 0.50 |
| ▸ | FLT4 | P35916 | 11/20 | 0.50 |
| ▸ | KDR | P35968 | 11/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836330 | 0.85 | FLT1 (0.50) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL7838561 | 0.80 | FLT1 (0.54) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL11223447 | 0.77 | EGFR (0.53) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL11155479 | 0.77 | MMP2 (0.49) | ALDH1A1CYP3A4SMN1; SMN2NPSR1TDP1 | |
| SCHEMBL25297441 | 0.73 | ALDH1A1 (0.57) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL3925835 | 0.72 | FLT1 (0.61) | FLT1FLT4KDREGFRERBB2 | |
| SCHEMBL11580067 | 0.72 | GAA (0.58) | ALDH1A1CYP3A4CYP2C19NPSR1TDP1 | |
| SCHEMBL28677877 | 0.71 | KDM4E (0.71) | EGFRERBB2ALDH1A1LMNATSHR | |
| SCHEMBL14427561 | 0.71 | MCOLN3 (0.67) | ALDH1A1LMNATSHRMAPTKDM4E | |
| SCHEMBL5004063 | 0.70 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |