Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340265 | 0.92 | ABCB1 (0.41) | ABCB1LMNAHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL7825264 | 0.88 | HSD17B10 (0.47) | NPC1RAB9ALMNAMAPK1HSD17B10 | |
| SCHEMBL7338364 | 0.84 | GPR139 (0.45) | NPC1LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7341748 | 0.83 | TACR1 (0.41) | ALDH1A1GPR139MEN1KMT2ATP53 | |
| SCHEMBL7836351 | 0.83 | RAB9A (0.42) | NPC1RAB9ALMNAMAPK1HSD17B10 | |
| SCHEMBL6778100 | 0.82 | ITGB3 (0.42) | AHRGPR139 | |
| SCHEMBL7825718 | 0.82 | TP53 (0.47) | ALDH1A1GPR139MEN1KMT2ATP53 | |
| SCHEMBL7339503 | 0.81 | KMT2A (0.42) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7823384 | 0.80 | ALDH1A1 (0.40) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7838138 | 0.80 | POLB (0.37) | NPC1RAB9AALDH1A1GPR139MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | claimed |