Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10449706 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL10451501 | 0.82 | MEN1 (0.39) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1713464 | 0.78 | CYP4F2 (0.44) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL530506 | 0.78 | CYP4F2 (0.44) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27897647 | 0.77 | MEN1 (0.36) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27949207 | 0.76 | MEN1 (0.38) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27880757 | 0.76 | MMP8 (0.36) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL981072 | 0.76 | DGAT1 (0.38) | — | |
| SCHEMBL16222521 | 0.74 | MEN1 (0.34) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL16222688 | 0.74 | MEN1 (0.34) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207446-B | Five-membered C-N linked aryl thioether and aryl sulfoxide derivatives as pest control agents | 拜耳作物科学股份公司 | 2020-11-13 | — | — | CN | disclosed |
| US-10206398-B2 | Five-membered C-N-attached aryl sulphide and aryl sulphoxide derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-19 | — | — | US | disclosed |
| EP-3230267-B1 | FIVE-MEMBERED C-N LINKED ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-09-26 | — | — | EP | disclosed |
| US-20170367333-A1 | FIVE-MEMBERED C-N-ATTACHED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-28 | — | — | US | disclosed |
| EP-3230267-A1 | FIVE-MEMBERED C-N BONDED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016091857-A1 | FIVE-MEMBERED C-N BONDED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-16 | — | — | WO | disclosed |
| EP-1137640-A1 | CYCLIC HYDRAZINE DERIVATIVES AS TNF-ALPHA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-04 | — | — | EP | disclosed |
| US-6281363-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; AUTOIMMUNE DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |
| WO-2000035885-A1 | CYCLIC HYDRAZINE DERIVATIVES AS TNF-ALPHA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170367333-A1 | FIVE-MEMBERED C-N-ATTACHED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PESTICIDES | DDT, ARSA, CYCS | MEN1 4610/4885KMT2A 3065/4885CYP4F2 204/4885 |
| US-10206398-B2 | Five-membered C-N-attached aryl sulphide and aryl sulphoxide derivatives as pesticides | DDT, ARSA, CYCS | MEN1 4610/4885KMT2A 3065/4885CYP4F2 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.