Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003914 | 0.83 | ALDH1A1 (0.56) | CNR2CNR1ALDH1A1NPC1RAB9A | |
| SCHEMBL78865 | 0.81 | ICMT (0.42) | CNR2CNR1ALDH1A1MAPTHTT | |
| SCHEMBL78476 | 0.81 | ICMT (0.42) | CNR2CNR1ALDH1A1HTTLMNA | |
| SCHEMBL90184 | 0.80 | CNR2 (0.56) | CNR2CNR1ALDH1A1MAPTHTT | |
| SCHEMBL21848866 | 0.80 | HTR6 (0.43) | CNR2CNR1ALDH1A1 | |
| SCHEMBL20655567 | 0.80 | POLB (0.49) | CNR2CNR1ALDH1A1 | |
| SCHEMBL4604311 | 0.79 | CNR2 (0.55) | CNR2CNR1ALDH1A1MAPTHTT | |
| SCHEMBL12048886 | 0.79 | CNR2 (0.55) | CNR2CNR1ALDH1A1MAPTHTT | |
| SCHEMBL13806318 | 0.79 | CNR2 (0.55) | CNR2CNR1ALDH1A1MAPTHTT | |
| SCHEMBL88821 | 0.78 | CNR2 (0.57) | CNR2CNR1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |