Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840803 | 0.89 | ATAD2 (0.38) | LMNAALDH1A1ATAD2P2RY2KDM4E | |
| SCHEMBL7488455 | 0.88 | ATAD2 (0.40) | LMNAALDH1A1ATAD2P2RY2KDM4E | |
| SCHEMBL7491592 | 0.85 | ALDH1A1 (0.45) | LMNAALDH1A1P2RY2KDM4EHSD17B10 | |
| SCHEMBL7486706 | 0.81 | P2RY2 (0.37) | LMNAALDH1A1ATAD2P2RY2KDM4E | |
| SCHEMBL7841473 | 0.81 | LMNA (0.37) | LMNAALDH1A1ATAD2P2RY2KDM4E | |
| SCHEMBL7840949 | 0.80 | P2RY2 (0.39) | LMNAALDH1A1P2RY2KDM4EHSD17B10 | |
| SCHEMBL7490690 | 0.79 | P2RY2 (0.40) | LMNAALDH1A1P2RY2KDM4EHSD17B10 | |
| SCHEMBL7491074 | 0.79 | P2RY2 (0.34) | LMNAALDH1A1ATAD2P2RY2KDM4E | |
| SCHEMBL7503494 | 0.76 | LMNA (0.33) | LMNAALDH1A1ATAD2P2RY2KDM4E | |
| SCHEMBL7495877 | 0.75 | P2RY2 (0.46) | LMNAALDH1A1P2RY2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984963-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-04-11 | — | — | EP | disclosed |