Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208082 | 0.88 | KMT2A (0.55) | ALDH1A1MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL11638233 | 0.83 | PTK2 (0.59) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6643211 | 0.79 | ALDH1A1 (0.53) | TSHRALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL6636910 | 0.79 | TSHR (0.46) | TSHRALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL7306619 | 0.79 | KMT2A (0.52) | ALDH1A1MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL15440489 | 0.79 | HPGD (0.53) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9396580 | 0.78 | MEN1 (0.48) | TSHRALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL8550652 | 0.78 | KMT2A (0.51) | ALDH1A1MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL9398335 | 0.77 | PKM (0.47) | TSHRALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL31469754 | 0.75 | MEN1 (0.50) | ALDH1A1MEN1KMT2AUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107973-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012514-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-03-09 | — | — | WO | disclosed |