Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.60 |
| ▸ | TGM2 | P21980 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410586 | 0.88 | MAPT (0.62) | TSHRRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL12230853 | 0.85 | TGM2 (0.53) | TSHRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL13412008 | 0.84 | KDM4E (0.56) | TSHRMEN1KMT2AMAPTTGM2 | |
| SCHEMBL13412007 | 0.84 | TGM2 (0.64) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL14407375 | 0.84 | TGM2 (0.55) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5037749 | 0.83 | TGM2 (0.67) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL8686785 | 0.82 | KMT2A (0.64) | TSHRRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4013632 | 0.82 | TSHR (0.67) | TSHRRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9877349 | 0.82 | TSHR (0.67) | TSHRRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7825125 | 0.82 | KMT2A (0.64) | TSHRRAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192953-A | Anticorrosive paint for outdoor metal components | 河南省阳光防腐涂装有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118955381-A | Pyrazole compound as well as preparation method and application thereof | 赣南师范大学 | 2024-11-15 | — | — | CN | claimed |
| CN-119192953-A | Anticorrosive paint for outdoor metal components | 河南省阳光防腐涂装有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-119192953-A | Anticorrosive paint for outdoor metal components | 河南省阳光防腐涂装有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-118955381-A | Pyrazole compound as well as preparation method and application thereof | 赣南师范大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-117263760-A | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-111936470-B | Amidopyrazoles useful as irreversible FGFR inhibitors | 上海奕拓医药科技有限责任公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-110317173-B | Amidopyrazoles useful as irreversible FGFR inhibitors | 上海奕拓医药科技有限责任公司 | 2022-10-11 | — | — | CN | disclosed |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| CN-111936470-A | Amidopyrazoles useful as FGFR irreversible inhibitors | 中国科学院上海有机化学研究所 | 2020-11-13 | — | — | CN | disclosed |
| US-20200062696-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RETICULON 4 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-02-27 | — | — | US | disclosed |
| US-20030022892-A1 | Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives | SPECTRUM PHARMACEUTICALS, INC. | 2003-01-30 | — | — | US | disclosed |
| US-20020198218-A1 | Synthesis and methods of use of tetrahydroindolone analogues and derivatives | SPECTRUM PHARMACEUTICALS, INC. | 2002-12-26 | — | — | US | disclosed |
| WO-2002085904-A1 | SNYTHESIS AND METHODS OF USE OF PURINE ANALOGUES AND DERIVATIVES | NEOTHERAPEUTICS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| WO-2002085856-A1 | SYNTHESIS AND METHODS OF USE OF TETRAHYDROINDOLONE ANALOGUES AND DERIVATIVES | NEOTHERAPEUTICS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-20020156277-A1 | Synthesis and methods of use of purine analogues and derivatives | NEO THERAPEUTICS, INC. | 2002-10-24 | — | — | US | disclosed |
| EP-0409565-A1 | Rubber composition useful for tires | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4940711-A | Antihypertensive N-piperazinylalkanoylanilides | RECORDATI, S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1990-07-10 | — | — | US | disclosed |
| EP-0120558-A1 | Antihypertensive N-piperazinylalkanoylanilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1984-10-03 | — | — | EP | disclosed |
| US-4021404-A | AMIDES, NATURAL AND SYNTHETIC RUBBERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062696-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RETICULON 4 | RTN4, RTN3, RCN1 | TSHR 4237/4885RAB9A 939/4885SMN1; SMN2 2138/4885 |
| US-20020198218-A1 | Synthesis and methods of use of tetrahydroindolone analogues and derivatives | CYP11B1, CYP11B2, CYP4A11 | TSHR 1910/4885RAB9A 2901/4885SMN1; SMN2 3619/4885 |
| US-20020156277-A1 | Synthesis and methods of use of purine analogues and derivatives | SLC29A1, ATIC, PNP | TSHR 2652/4885RAB9A 1809/4885SMN1; SMN2 1500/4885 |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | RNF114, RNF4, RNF168 | TSHR 4065/4885RAB9A 2224/4885SMN1; SMN2 1834/4885 |
| US-20030022892-A1 | Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives | DRD4, DRD2, DRD1 | TSHR 3517/4885RAB9A 1483/4885SMN1; SMN2 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.