Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088051 | 0.93 | GRIN1 (0.45) | GRIN1GRIN2BGLATPH1TPH2 | |
| SCHEMBL7851564 | 0.80 | TYMP (0.32) | DRD1 | |
| SCHEMBL8206122 | 0.80 | DAO (0.36) | — | |
| SCHEMBL7844829 | 0.80 | NR3C1 (0.40) | GRIN1GRIN2B | |
| SCHEMBL6086864 | 0.79 | HPGD (0.44) | TLR7 | |
| SCHEMBL6087851 | 0.79 | GRIN1 (0.45) | GRIN1GRIN2BTPH1TPH2NOX4 | |
| SCHEMBL6087138 | 0.78 | DRD1 (0.36) | TPH1TPH2DRD1TLR7 | |
| SCHEMBL6086584 | 0.78 | DCTPP1 (0.34) | TPH1TPH2DRD1TLR7 | |
| SCHEMBL7850609 | 0.78 | GRIN1 (0.38) | GRIN1GRIN2BTPH1TPH2 | |
| SCHEMBL6086356 | 0.77 | PDE10A (0.42) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |