Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | RPA1 | P27694 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087165 | 0.85 | PDE10A (0.37) | PDE10ABRD4CYP1A2DPP4CYP3A4 | |
| SCHEMBL6087014 | 0.84 | DAO (0.46) | PDE10ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL6086584 | 0.83 | DCTPP1 (0.34) | KDM4EALDH1A1DRD1 | |
| SCHEMBL6087138 | 0.83 | DRD1 (0.36) | KDM4EALDH1A1DRD1 | |
| SCHEMBL6088051 | 0.83 | GRIN1 (0.45) | DRD1 | |
| SCHEMBL6086864 | 0.82 | HPGD (0.44) | BRD4CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6088271 | 0.82 | NPBWR1 (0.35) | PDE10ACYP1A2KDM4EALDH1A1DRD1 | |
| SCHEMBL6087657 | 0.81 | TP53 (0.39) | ALDH1A1DRD1 | |
| SCHEMBL6086514 | 0.80 | PDE10A (0.40) | PDE10ABRD4DPP4CYP3A4FAP | |
| SCHEMBL6087616 | 0.80 | PDE10A (0.40) | PDE10ABRD4CYP1A2DPP4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |